Healthy nervous– and musculoskeletal systems are key determinants for performing activities of daily living. Our goal is to understand the interaction and crosstalk between these two systems. Our research examines changes in structure, function, and physiology that occur in neural, skeletal muscle and connective tissues as a result of muscle disuse, injury and chronic pain.
West et al., Low responders to endurance training exhibit impaired hypertrophy and divergent biological process responses in rat skeletal muscle, Exp. Physiology 2021; 1– 12. https://doi.org/10.1113/EP089301
Duarte FCK, Hurtig M, Clark A, Simpson J, Srbely JZ, Association between naturally occurring spine osteoarthritis in geriatric rats and neurogenic inflammation within neurosegmentally linked skeletal muscle, Experimental Gerontology, 2019 118:31-38
West et al., The exercise‐induced biochemical milieu enhances collagen content and tensile strength of engineered ligaments. J Physiol, 2015, 593: 4665-4675. https://doi.org/10.1113/JP270737